USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: DBNL_HUMAN USC-OGP 2-DE database:  DBNL_HUMAN DBNL_HUMAN General information about the entry View entry in simple text format Entry name DBNL_HUMAN Primary accession number Q9HBN8 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Drebrin-like protein; AltName: Full=Cervical SH3P7; AltName: Full=Cervical mucin-associated protein; AltName: Full=Drebrin-F; AltName: Full=HPK1-interacting protein of 55 kDa; Short=HIP-55; AltName: Full=SH3 domain-containing protein 7;. Gene name Name=DBNL Synonyms=CMAP, SH3P7 ORFNames=PP5423 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0354: pI=5.02; Mw=51969 Cross-references UniProtKB/Swiss-Prot Q9UJU6; DBNL_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name DBNL_HUMAN Primary accession number Q9UJU6 Secondary accession number(s) A4D2I9 B4DDP6 B4DEM2 C9J7P1 P84070 Q6IAI8 Q96F30 Q96K74 Q9HBN8 Q9NR72 Sequence was last modified on  May 1, 2000 (version 1) Annotations were last modified on  March 15, 2017 (version 156) Name and origin of the protein Description RecName: Full=Drebrin-like protein; AltName: Full=Cervical SH3P7; AltName: Full=Cervical mucin-associated protein; AltName: Full=Drebrin-F; AltName: Full=HPK1-interacting protein of 55 kDa; Short=HIP-55; AltName: Full=SH3 domain-containing protein 7; Gene name Name=DBNL Synonyms=CMAP, SH3P7 ORFNames=PP5423 Encoded on Name=DBNL; Synonyms=CMAP, SH3P7; ORFNames=PP5423 Keywords 3D-structure; Acetylation; Actin-binding; Adaptive immunity; Alternative splicing; Cell junction; Cell membrane; Cell projection; Coiled coil; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Endocytosis; Endosome; Golgi apparatus; Immunity; Membrane; Phosphoprotein; Reference proteome; SH3 domain; Synapse; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF197060; AAF13701.1; -; mRNA EMBL AF077353; AAF80228.1; -; mRNA EMBL AF250287; AAF81273.1; -; mRNA EMBL AF151364; AAG13120.1; -; mRNA EMBL AF218020; AAG17262.2; -; mRNA EMBL AK027367; BAB55065.1; -; mRNA EMBL AK293279; BAG56807.1; -; mRNA EMBL AK293698; BAG57133.1; -; mRNA EMBL CR457167; CAG33448.1; -; mRNA EMBL AC017116; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH236960; EAL23770.1; -; Genomic_DNA EMBL CH471128; EAW61132.1; -; Genomic_DNA EMBL BC011677; AAH11677.1; -; mRNA EMBL BC031687; AAH31687.1; -; mRNA CCDS CCDS34622.1; -. [Q9UJU6-2]; . CCDS CCDS34623.1; -. [Q9UJU6-1]; . CCDS CCDS47579.1; -. [Q9UJU6-3]; . CCDS CCDS64633.1; -. [Q9UJU6-4]; . CCDS CCDS64634.1; -. [Q9UJU6-5]; . RefSeq NP_001014436.1; NM_001014436.2. [Q9UJU6-1]; . RefSeq NP_001116428.1; NM_001122956.1. [Q9UJU6-3]; . RefSeq NP_001271242.1; NM_001284313.1. [Q9UJU6-5]; . RefSeq NP_001271244.1; NM_001284315.1. [Q9UJU6-4]; . RefSeq NP_054782.2; NM_014063.6. [Q9UJU6-2]; . UniGene Hs.436500; -; . PDB 1X67; NMR; -; A=1-133 PDBsum 1X67; -; . ProteinModelPortal Q9UJU6; -; . SMR Q9UJU6; -; . BioGrid 118809; 50; . IntAct Q9UJU6; 8; . MINT MINT-1474845; -; . STRING 9606.ENSP00000417653; -; . iPTMnet Q9UJU6; -; . PhosphoSitePlus Q9UJU6; -; . BioMuta DBNL; -; . DMDM 51316115; -; . OGP Q9UJU6; -; . EPD Q9UJU6; -; . PaxDb Q9UJU6; -; . PeptideAtlas Q9UJU6; -; . PRIDE Q9UJU6; -; . TopDownProteomics Q9UJU6-2; -. [Q9UJU6-2]; . DNASU 28988; -; . Ensembl ENST00000440166; ENSP00000415173; ENSG00000136279. [Q9UJU6-5]; . Ensembl ENST00000448521; ENSP00000411701; ENSG00000136279. [Q9UJU6-1]; . Ensembl ENST00000456905; ENSP00000416421; ENSG00000136279. [Q9UJU6-6]; . Ensembl ENST00000468694; ENSP00000417653; ENSG00000136279. [Q9UJU6-3]; . Ensembl ENST00000490734; ENSP00000417749; ENSG00000136279. [Q9UJU6-4]; . Ensembl ENST00000494774; ENSP00000419992; ENSG00000136279. [Q9UJU6-2]; . GeneID 28988; -; . KEGG hsa:28988; -; . UCSC uc003tjo.5; human. [Q9UJU6-1]; . CTD 28988; -; . DisGeNET 28988; -; . GeneCards DBNL; -; . GeneCards MIR6837; -; . HGNC HGNC:2696; DBNL; . HPA HPA020265; -; . HPA HPA027735; -; . MIM 610106; gene; . neXtProt NX_Q9UJU6; -; . OpenTargets ENSG00000136279; -; . PharmGKB PA27164; -; . eggNOG KOG3655; Eukaryota; . eggNOG ENOG410XRVX; LUCA; . GeneTree ENSGT00530000062953; -; . HOGENOM HOG000008567; -; . HOVERGEN HBG051316; -; . InParanoid Q9UJU6; -; . KO K20520; -; . OMA FQDTGPQ; -; . OrthoDB EOG091G05KP; -; . PhylomeDB Q9UJU6; -; . TreeFam TF318935; -; . Reactome R-HSA-264870; Caspase-mediated cleavage of cytoskeletal proteins; . Reactome R-HSA-6794361; Interactions of neurexins and neuroligins at synapses; . Reactome R-HSA-6798695; Neutrophil degranulation; . SignaLink Q9UJU6; -; . SIGNOR Q9UJU6; -; . ChiTaRS DBNL; human; . EvolutionaryTrace Q9UJU6; -; . GeneWiki Drebrin-like; -; . GenomeRNAi 28988; -; . PMAP-CutDB Q9UJU6; -; . PRO PR:Q9UJU6; -; . Proteomes UP000005640; Chromosome 7; . Bgee ENSG00000136279; -; . CleanEx HS_DBNL; -; . ExpressionAtlas Q9UJU6; baseline and differential; . Genevisible Q9UJU6; HS; . GO GO:0005938; C:cell cortex; ISS:UniProtKB; . GO GO:0030054; C:cell junction; IEA:UniProtKB-KW; . GO GO:0030665; C:clathrin-coated vesicle membrane; IEA:UniProtKB-SubCell; . GO GO:0005737; C:cytoplasm; ISS:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0030425; C:dendrite; IEA:Ensembl; . GO GO:0005769; C:early endosome; IEA:UniProtKB-SubCell; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell; . GO GO:0030027; C:lamellipodium; ISS:UniProtKB; . GO GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; . GO GO:0002102; C:podosome; ISS:UniProtKB; . GO GO:0014069; C:postsynaptic density; IEA:Ensembl; . GO GO:0001726; C:ruffle; ISS:UniProtKB; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:1904724; C:tertiary granule lumen; TAS:Reactome; . GO GO:0003779; F:actin binding; ISS:UniProtKB; . GO GO:0051015; F:actin filament binding; ISS:UniProtKB; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0008047; F:enzyme activator activity; TAS:ProtInc; . GO GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc; . GO GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW; . GO GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0071800; P:podosome assembly; ISS:UniProtKB; . GO GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB; . GO GO:0006898; P:receptor-mediated endocytosis; IEA:InterPro; . GO GO:0097178; P:ruffle assembly; IEA:InterPro; . GO GO:0007416; P:synapse assembly; ISS:UniProtKB; . Gene3D 3.40.20.10; -; 1; . InterPro IPR002108; ADF-H; . InterPro IPR029006; ADF-H/Gelsolin-like_dom; . InterPro IPR029923; Dbnl; . InterPro IPR001452; SH3_domain; . PANTHER PTHR10829:SF30; PTHR10829:SF30; 1; . Pfam PF00241; Cofilin_ADF; 1; . Pfam PF14604; SH3_9; 1; . SMART SM00102; ADF; 1; . SMART SM00326; SH3; 1; . SUPFAM SSF50044; SSF50044; 1; . PROSITE PS51263; ADF_H; 1; . PROSITE PS50002; SH3; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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